| Customization: | Available |
|---|---|
| Application: | Internal Medicine |
| Usage Mode: | For oral administration |
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Indications:
The prevention and treatment of scurvy, or other conditions requiring vitamin C supplementation, where the deficiency is acute or oral administration is difficult.
Dosage and Administration:
For adults:
0.5 to 1g daily for scurvy, 200 to 500mg daily for preventative therapy
For children:
100 to 300mg daily for curative purposes, or 30mg daily for protective treatment.
For elderly:
No special dosage requirements have been suggested.
Precautions & Warning:
Vitamin C should be given with care to patients with underlying renal failure due to the risk of formation of renal oxalate calculi. Tolerance may be induced in patients taking high doses.
Large doses of vitamin C have resulted in haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Contra-indications:
Hyperoxaluria
Drug interactions:
Drugs which induce tissue desaturation of vitamin C include aspirin, nicotine from cigarettes, alcohol, several appetite suppressants, iron, phenytoin, some anti-convulsant drugs, the oestrogen component of oral contraceptives and tetracycline.
Undesirable effects:
Large doses may cause gastrointestinal disorders including diarrhoea. Large doses may also result in hyperoxaluria and renal oxalate calculi may form if the urine becomes acidic.
Storage instructions:
Do not store above 25°C. Keep the vial in the outer carton in order to protect from light.
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